Recent publications
1. Real time, in vivo measurement of neuronal and peripheral clocks in Drosophila melanogaster.
Johnstone PS, Ogueta M, Akay O, Top I, Syed S, Stanewsky R, Top D.
Elife. 2022 Oct 3;11:e77029. doi: 10.7554/eLife.77029.
2. Integration of Circadian Clock Information in the Drosophila Circadian Neuronal Network.
Ahmad M, Li W, Top D.
J Biol Rhythms. 2021 Jun;36(3):203-220. doi: 10.1177/0748730421993953
3. Characterization of SETD1A haploinsufficiency in humans and Drosophila defines a novel neurodevelopmental syndrome.
Kummeling J, Stremmelaar DE, Raun N, et al.
Mol Psychiatry. 2021 Jun;26(6):2013-2024. doi: 10.1038/s41380-020-0725-5
4. CK1/Doubletime activity delays transcription activation in the circadian clock.
Top D, O'Neil JL, Merz GE, Dusad K, Crane BR, Young MW.
Elife. 2018 Apr 3;7. pii: e32679. doi: 10.7554/eLife.32679.
5. Circadian clock activity of cryptochrome relies on tryptophan-mediated photoreduction.
Lin C, Top D, Manahan CC, Young MW, Crane BR.
Proc Natl Acad Sci U S A. 2018 Apr 10;115(15):3822-3827. doi: 10.1073/pnas.1719376115.
6. Coordination between Differentially Regulated Circadian Clocks Generates Rhythmic Behavior.
Top D, Young MW.
Cold Spring Harb Perspect Biol. 2018 Jul 2;10(7). pii: a033589. doi: 10.1101/cshperspect.a033589. Review.
7. Changes in active site histidine hydrogen bonding trigger cryptochrome activation.
Ganguly A, Manahan CC, Top D, Yee EF, Lin C, Young MW, Thiel W, Crane BR.
Proc Natl Acad Sci U S A. 2016 Sep 6;113(36):10073-8. doi: 10.1073/pnas.1606610113.
8. GSK-3 and CK2 Kinases Converge on Timeless to Regulate the Master Clock.
Top D, Harms E, Syed S, Adams EL, Saez L.
Cell Rep. 2016 Jul 12;16(2):357-367. doi: 10.1016/j.celrep.2016.06.005.
9. Flavin reduction activates Drosophila cryptochrome.
Vaidya AT, Top D, Manahan CC, Tokuda JM, Zhang S, Pollack L, Young MW, Crane BR.
Proc Natl Acad Sci U S A. 2013 Dec 17;110(51):20455-60. doi: 10.1073/pnas.1313336110.
10. Updated structure of Drosophila cryptochrome.
Levy C, Zoltowski BD, Jones AR, Vaidya AT, Top D, Widom J, Young MW, Scrutton NS, Crane BR, Leys D.
Nature. 2013 Mar 21;495(7441):E3-4. doi: 10.1038/nature11995.
11. Structure of full-length Drosophila cryptochrome.
Zoltowski BD, Vaidya AT, Top D, Widom J, Young MW, Crane BR.
Nature. 2011 Nov 13;480(7377):396-9. doi: 10.1038/nature10618.